SCHEMBL9236759

SCHEMBL9236759

CC1=CCC2CC1CCC2C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8049213 0.73
SCHEMBL8047885 0.67 TSHR (0.32) TSHRMAPK1
SCHEMBL9299698 0.66
SCHEMBL10793462 0.65 TP53 (0.34) TSHR
SCHEMBL10792982 0.65 TP53 (0.34) TSHR
SCHEMBL10792555 0.65 TP53 (0.34) TSHR
SCHEMBL10792094 0.64 HSP90AA1 (0.30)
SCHEMBL11492325 0.64 TSHR (0.30) TSHRMAPK1
SCHEMBL9298918 0.64
SCHEMBL15957291 0.63 TSHR (0.31) TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0646565-A1 Substituted 2,6-Dimethylbicyclo 3,3,1 non-6-enes, processes for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1995-04-05 EP claimed
US-5346884-A Substituted 2,6-dimethylbicyclo[3,3,1]non-6-enes, processes for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-09-13 US claimed
EP-0646565-A1 Substituted 2,6-Dimethylbicyclo 3,3,1 non-6-enes, processes for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1995-04-05 EP disclosed
EP-0646565-A1 Substituted 2,6-Dimethylbicyclo 3,3,1 non-6-enes, processes for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1995-04-05 EP disclosed
EP-0646565-A1 Substituted 2,6-Dimethylbicyclo 3,3,1 non-6-enes, processes for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1995-04-05 EP disclosed
US-5367092-A Compounds for perfumes formed by heating cyclohexene aldehydes INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-11-22 US disclosed
US-5367092-A Compounds for perfumes formed by heating cyclohexene aldehydes INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-11-22 US disclosed
US-5367092-A Compounds for perfumes formed by heating cyclohexene aldehydes INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-11-22 US disclosed
US-5346884-A Substituted 2,6-dimethylbicyclo[3,3,1]non-6-enes, processes for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-09-13 US disclosed
US-5346884-A Substituted 2,6-dimethylbicyclo[3,3,1]non-6-enes, processes for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-09-13 US disclosed
US-5346884-A Substituted 2,6-dimethylbicyclo[3,3,1]non-6-enes, processes for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1994-09-13 US disclosed