Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237255 | 1.00 | MAPT (0.47) | MAPTTHRBSMN1; SMN2RARBRAB9A | |
| SCHEMBL9237594 | 0.93 | RARB (0.53) | MAPTTHRBSMN1; SMN2RARBRAB9A | |
| SCHEMBL9237597 | 0.93 | RARB (0.53) | MAPTTHRBSMN1; SMN2RARBRAB9A | |
| SCHEMBL9239809 | 0.91 | RARB (0.58) | MAPTTHRBSMN1; SMN2RARBRAB9A | |
| SCHEMBL9239813 | 0.91 | RARB (0.58) | MAPTTHRBSMN1; SMN2RARBRAB9A | |
| SCHEMBL9240007 | 0.90 | RARB (0.60) | MAPTTHRBSMN1; SMN2RARBRAB9A | |
| SCHEMBL9236919 | 0.90 | RARB (0.60) | MAPTTHRBSMN1; SMN2RARBRAB9A | |
| SCHEMBL9239151 | 0.90 | RARB (0.60) | MAPTTHRBSMN1; SMN2RARBRAB9A | |
| SCHEMBL9238268 | 0.90 | RARB (0.60) | MAPTTHRBSMN1; SMN2RARBRAB9A | |
| SCHEMBL9238267 | 0.90 | RARB (0.60) | MAPTTHRBSMN1; SMN2RARBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389290-A | Ferroelectric liquid crystalline materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| US-5089168-A | Stable ferroelectric liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-02-18 | — | — | US | disclosed |