SCHEMBL9237607

SCHEMBL9237607

Cc1cccc(C)c1-c1ccccc1C1=CC(=O)NC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.42
MYC P01106 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
POLB P06746 2/20 0.39
GSK3B P49841 1/20 0.36
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
PARP1 P09874 1/20 0.36
PARP10 Q53GL7 1/20 0.36
PARP11 Q9NR21 1/20 0.36
PRKD3 O94806 1/20 0.35
PRKCG P05129 1/20 0.35
PRKCB P05771 1/20 0.35
PRKCA P17252 1/20 0.35
PRKCH P24723 1/20 0.35
PRKCI P41743 1/20 0.35
PRKCE Q02156 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2313651 0.88 DAO (0.43) DAOMYCCA1CA2CA7
SCHEMBL711313 0.86 DAO (0.43) DAOCA1CA2CA7CA9
Ammonia Solution, Strong SCHEMBL27993531 0.84 DAO (0.42) DAOCA1CA2CA7CA9
SCHEMBL505505 0.84 DAO (0.40) DAOCA1CA2CA7CA9
SCHEMBL121405 0.84 GSK3B (0.50) CA1CA2CA7CA9POLB
SCHEMBL27664385 0.84 GSK3B (0.50) CA1CA2CA7CA9POLB
SCHEMBL710773 0.83 DAO (0.44) DAOCA1CA2CA7CA9
SCHEMBL11120799 0.82 GSK3B (0.48) CA1CA2CA7CA9POLB
SCHEMBL29011874 0.81 GSK3B (0.40) DAOPOLBGSK3BPARP1PRKD3
SCHEMBL8847907 0.80 DAO (0.40) DAOCA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628578-A3 2,6-Dimethylphenylphenymaleimide as comonomer in the copolymerisation of styrene or vinyl chlorid. CHEMIE LINZ GMBH (AT) 1995-09-27 EP disclosed
EP-0628578-A2 2,6-Dimethylphenylphenymaleimide as comonomer in the copolymerisation of styrene or vinyl chlorid DSM Chemie Linz GmbH (AT) 1994-12-14 EP disclosed