Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584378 | 0.94 | KDM4E (0.54) | KDM4EPKMHPGDGLSGPR119 | |
| SCHEMBL28063864 | 0.92 | KDM4E (0.53) | KDM4EPKMHPGDGLSGPR119 | |
| SCHEMBL9236134 | 0.92 | HPGD (0.61) | KDM4EPKMDDB1CRBNHPGD | |
| SCHEMBL9234957 | 0.92 | HPGD (0.61) | KDM4EPKMDDB1CRBNHPGD | |
| SCHEMBL13812235 | 0.90 | HPGD (0.60) | KDM4EPKMDDB1CRBNHPGD | |
| SCHEMBL23212559 | 0.88 | HPGD (0.55) | KDM4EPKMHPGDGLSGPR119 | |
| SCHEMBL4649476 | 0.88 | DDB1 (0.50) | KDM4EPKMDDB1CRBNHPGD | |
| SCHEMBL28573962 | 0.88 | KDM4E (0.50) | KDM4EPKMDDB1CRBNHPGD | |
| SCHEMBL9236069 | 0.86 | KDM4E (0.48) | KDM4EPKMDDB1CRBNHPGD | |
| SCHEMBL13812230 | 0.86 | DDB1 (0.48) | KDM4EPKMDDB1CRBNHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638553-A1 | Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs | Dr. Karl Thomae GmbH (DE) | 1995-02-15 | — | — | EP | disclosed |