Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9239093 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL11707997 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL11812000 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL9392095 | 0.83 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL2067896 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL2067894 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL11810271 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL11709538 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 | |
| SCHEMBL9286167 | 0.78 | — | — | |
| SCHEMBL28058050 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679397-A2 | Use of substituted amines for the treatment of cerebral insufficiencies | BAYER AG (DE) | 1995-11-02 | — | — | EP | claimed |
| EP-0679397-A2 | Use of substituted amines for the treatment of cerebral insufficiencies | BAYER AG (DE) | 1995-11-02 | — | — | EP | disclosed |