Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL266622 | 0.77 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1CA2 | |
| SCHEMBL23268490 | 0.73 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1CA2 | |
| SCHEMBL6359533 | 0.72 | CHRNB4 (0.47) | CHRNB4CHRNA3 | |
| SCHEMBL25703969 | 0.72 | MEN1 (0.49) | MEN1KMT2ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL25706673 | 0.72 | MEN1 (0.49) | MEN1KMT2ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL23268480 | 0.72 | MEN1 (0.55) | MEN1KMT2ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL23268487 | 0.71 | MEN1 (0.58) | MEN1KMT2AKDM4EALDH1A1CA2 | |
| SCHEMBL23268494 | 0.71 | MEN1 (0.54) | MEN1KMT2ACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL31172738 | 0.71 | MEN1 (0.58) | MEN1KMT2AKDM4EALDH1A1CA2 | |
| SCHEMBL25705273 | 0.71 | MEN1 (0.54) | MEN1KMT2ACHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657455-A1 | Epi-epibatidine derivatives, a process and intermediates for preparing them and epi-epibatidine and medicaments containing the epi-epibatidine derivatives and/or epi-epibatidine and the use of them | EGIS GYOGYSZERGYAR (HU) | 1995-06-14 | — | — | EP | disclosed |