Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9239031 | 1.00 | RARB (0.47) | RARBTP53TSHRRAB9ANPC1 | |
| SCHEMBL9240223 | 1.00 | RARB (0.47) | RARBTP53TSHRRAB9ANPC1 | |
| SCHEMBL9240395 | 1.00 | RARB (0.47) | RARBTP53TSHRRAB9ANPC1 | |
| SCHEMBL9237326 | 0.99 | RARB (0.45) | RARBTP53TSHRRAB9ANPC1 | |
| SCHEMBL9239845 | 0.95 | NPC1 (0.48) | RARBTSHRRAB9ANPC1KDM4E | |
| SCHEMBL9237111 | 0.92 | ACACB (0.43) | RARBRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL9235133 | 0.90 | RARB (0.46) | RARBTP53TSHRRAB9ANPC1 | |
| SCHEMBL9240993 | 0.90 | RARB (0.46) | RARBTP53TSHRRAB9ANPC1 | |
| SCHEMBL9237542 | 0.90 | RARB (0.46) | RARBTP53TSHRRAB9ANPC1 | |
| SCHEMBL9238192 | 0.90 | RARB (0.46) | RARBTP53TSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389290-A | Ferroelectric liquid crystalline materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| US-5089168-A | Stable ferroelectric liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-02-18 | — | — | US | disclosed |