SCHEMBL9239302

SCHEMBL9239302

Cc1cc(OC(F)(F)C(F)Cl)ccc1C(=S)c1cnoc1C1CC1

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 5/20 0.48
EPHX2 P34913 2/20 0.38
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
CRACR2A Q9BSW2 1/20 0.32
ACACB O00763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9238084 0.93 DHODH (0.49) DHODHEPHX2CRACR2A
SCHEMBL9115855 0.86 DHODH (0.45) DHODHEPHX2LMNAACACB
SCHEMBL9113774 0.81 DHODH (0.47) DHODHEPHX2LMNACRACR2AACACB
SCHEMBL9239856 0.78 DHODH (0.42) DHODHEPHX2LMNAPOLBCRACR2A
SCHEMBL9280090 0.77 DHODH (0.42) DHODHLMNA
SCHEMBL9114628 0.77 DHODH (0.44) DHODHLMNACRACR2A
SCHEMBL9238887 0.77 DHODH (0.43) DHODHLMNACRACR2A
SCHEMBL9116692 0.76 DHODH (0.55) DHODHEPHX2CRACR2A
SCHEMBL9117466 0.75 DHODH (0.42) DHODHLMNACRACR2A
SCHEMBL9116360 0.75 DHODH (0.42) DHODHLMNAPOLBCRACR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995022903-A1 NEW PESTICIDAL METHOD RHONE-POULENC AGROCHIMIE (FR) 1995-08-31 WO disclosed