Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | P2RY10 | O00398 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28669229 | 0.91 | LPAR3 (0.47) | LPAR3LPAR1LPAR2NPC1POLB | |
| SCHEMBL28655744 | 0.91 | LPAR3 (0.47) | LPAR3LPAR1LPAR2NPC1POLB | |
| SCHEMBL6573454 | 0.91 | LPAR3 (0.47) | LPAR3LPAR1LPAR2CETPMEN1 | |
| SCHEMBL11404885 | 0.91 | LPAR3 (0.47) | LPAR3LPAR1LPAR2NPC1POLB | |
| SCHEMBL28660409 | 0.91 | LPAR3 (0.47) | LPAR3LPAR1LPAR2NPC1POLB | |
| SCHEMBL28669221 | 0.91 | LPAR3 (0.47) | LPAR3LPAR1LPAR2NPC1POLB | |
| SCHEMBL10898774 | 0.90 | LPAR3 (0.46) | LPAR3LPAR1LPAR2CETPMEN1 | |
| SCHEMBL10898761 | 0.90 | LPAR3 (0.46) | LPAR3LPAR1LPAR2CETPMEN1 | |
| SCHEMBL28929453 | 0.89 | LPAR3 (0.45) | LPAR3LPAR1LPAR2CETPMEN1 | |
| SCHEMBL28150352 | 0.89 | P2RY10 (0.50) | LPAR3LPAR1LPAR2P2RY10GPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387352-A | Phosphorus-containing compositions | ETHYL CORPORATION (US) | 1995-02-07 | — | — | US | claimed |
| US-5387352-A | Phosphorus-containing compositions | ETHYL CORPORATION (US) | 1995-02-07 | — | — | US | disclosed |