SCHEMBL9239882

SCHEMBL9239882

CCCCCCCCOC(=O)C=CC(=O)OCCC[Si](C)(C)C

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.67
ATM Q13315 1/20 0.63
MAPT P10636 1/20 0.49
RAB9A P51151 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
NAAA Q02083 1/20 0.47
APP P05067 4/20 0.47
PRKCA P17252 2/20 0.46
TSHR P16473 2/20 0.46
HPGD P15428 1/20 0.46
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
EPHX1 P07099 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9239873 1.00 HCAR2 (0.67) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL373595 0.89 ATM (0.59) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL4630430 0.89 ATM (0.59) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL7780534 0.87 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL1305378 0.87 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL356935 0.87 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL42963 0.87 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL18209632 0.87 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9318682 0.87 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL440694 0.87 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434362-B1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution TOMEI SANGYO KK (JP) 1995-03-22 EP disclosed
EP-0433046-B1 Polymer-type polymerization initiator TOMEI SANGYO KK (JP) 1994-08-10 EP disclosed
US-5206298-A GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE TOMEI SANGYO KABUSHIKI KAISHA (JP) 1993-04-27 US disclosed
US-5134213-A N-Vinyllactam-Monoperoxyfumarate Terpolymer TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-07-28 US disclosed
US-5082912-A For graft polymerization, surfactants TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-01-21 US disclosed
EP-0434362-A1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-26 EP disclosed
EP-0433046-A2 Polymer-type polymerization initiator Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-19 EP disclosed