Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9241324 | 0.95 | NPC1 (0.49) | MAPTNPSR1NPC1RAB9AHSD17B10 | |
| SCHEMBL10721844 | 0.94 | RARB (0.45) | MAPTNPSR1NPC1RAB9AHSD17B10 | |
| SCHEMBL9239316 | 0.94 | NPC1 (0.44) | MAPTNPSR1L3MBTL1NPC1RAB9A | |
| SCHEMBL9237134 | 0.93 | NPC1 (0.47) | MAPTNPSR1NPC1RAB9AHSD17B10 | |
| SCHEMBL9235055 | 0.92 | RARB (0.47) | MAPTNPSR1NPC1RAB9AHSD17B10 | |
| SCHEMBL9236910 | 0.92 | RARB (0.47) | MAPTNPSR1NPC1RAB9AHSD17B10 | |
| SCHEMBL9240654 | 0.92 | RARB (0.47) | MAPTNPSR1NPC1RAB9AHSD17B10 | |
| SCHEMBL9238833 | 0.92 | RARB (0.47) | MAPTNPSR1NPC1RAB9AHSD17B10 | |
| SCHEMBL9239932 | 0.92 | NPC1 (0.48) | MAPTNPSR1L3MBTL1NPC1RAB9A | |
| SCHEMBL9241328 | 0.90 | NPC1 (0.49) | MAPTNPSR1NPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389290-A | Ferroelectric liquid crystalline materials | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| US-5089168-A | Stable ferroelectric liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-02-18 | — | — | US | disclosed |
| EP-0220297-B1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1991-12-11 | — | — | EP | disclosed |
| US-4834904-A | FERROELECTRIC LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-05-30 | — | — | US | disclosed |