Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9241966 | 1.00 | HCAR2 (0.46) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL9245882 | 0.88 | HCAR2 (0.43) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL9245890 | 0.88 | HCAR2 (0.43) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL9244678 | 0.83 | HCAR2 (0.52) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL6304123 | 0.83 | HCAR2 (0.52) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL9241469 | 0.81 | HCAR2 (0.46) | HCAR2ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL9241475 | 0.81 | HCAR2 (0.46) | HCAR2ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL9245888 | 0.80 | HCAR2 (0.48) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL9240319 | 0.80 | HCAR2 (0.48) | HCAR2CA12CA1CA2CA7 | |
| SCHEMBL9240325 | 0.80 | HCAR2 (0.48) | HCAR2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434362-B1 | Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution | TOMEI SANGYO KK (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5206298-A | GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1993-04-27 | — | — | US | disclosed |
| US-5134213-A | N-Vinyllactam-Monoperoxyfumarate Terpolymer | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-07-28 | — | — | US | disclosed |
| US-5082912-A | For graft polymerization, surfactants | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0434362-A1 | Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution | Tomei Sangyo Kabushiki Kaisha (JP) | 1991-06-26 | — | — | EP | disclosed |