Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247425 | 0.94 | HCAR2 (0.45) | TSHRHPGDHCAR2ALDH1A1NAAA | |
| SCHEMBL5464973 | 0.88 | TSHR (0.59) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| Acrylic Acid Ethyl Ester SCHEMBL17956579 | 0.84 | TSHR (0.44) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| SCHEMBL978390 | 0.83 | TSHR (0.67) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| SCHEMBL9247607 | 0.82 | HCAR2 (0.55) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| SCHEMBL971536 | 0.82 | TSHR (0.55) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| Acetic Acid SCHEMBL7449617 | 0.82 | TSHR (0.61) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| SCHEMBL10347411 | 0.82 | HCAR2 (0.51) | TSHRHCAR2ALDH1A1ATMNAAA | |
| SCHEMBL10347417 | 0.82 | HCAR2 (0.51) | TSHRHCAR2ALDH1A1ATMNAAA | |
| SCHEMBL7934372 | 0.82 | TSHR (0.64) | TSHRHPGDHCAR2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393529-A | Sustained release | LTS LOHMANN THERAPIE-SYSTEME GMBH & CO. KG (DE) | 1995-02-28 | — | — | US | disclosed |