SCHEMBL9242011

SCHEMBL9242011

COc1ccc(Cc2nc3nc(N)[nH]c(=O)c3[nH]2)cc1

nearest known ligand 0.70

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PNP P00491 7/20 0.70
TYMS P04818 1/20 0.49
FGFR1 P11362 2/20 0.48
FGFR2 P21802 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3303807 0.87 PNP (0.77) PNPFGFR1FGFR2
SCHEMBL17186462 0.86 PNP (0.52) PNPTYMSFGFR1FGFR2
Hydrochloric Acid SCHEMBL17186489 0.85 PNP (0.75) PNPFGFR1FGFR2
SCHEMBL985175 0.84 PNP (0.77) PNPFGFR1FGFR2
SCHEMBL3021038 0.83 PNP (0.75) PNPFGFR1FGFR2
SCHEMBL3310268 0.83 PNP (0.75) PNPTYMSFGFR1FGFR2
SCHEMBL3308558 0.83 PNP (0.75) PNPTYMSFGFR1FGFR2
Hydrochloric Acid SCHEMBL2777605 0.83 PNP (0.75) PNPFGFR1FGFR2
SCHEMBL1533546 0.83 PNP (0.75) PNP
SCHEMBL18248 0.82 PNP (1.00) PNPFGFR1FGFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7278146-A None JP disclosed
JP-H07278146-A BENZYLGUANINE DERIVATIVE TOAGOSEI CO LTD 1995-10-24 JP disclosed