Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27270770 | 0.97 | OR51E2 (0.46) | OR51E2GPR84FFAR1SMN1; SMN2TET2 | |
| Acetone SCHEMBL11022562 | 0.94 | OR51E2 (0.48) | OR51E2GPR84FFAR1SMN1; SMN2TET2 | |
| SCHEMBL15355768 | 0.94 | — | — | |
| SCHEMBL15717118 | 0.94 | OR51E2 (0.53) | OR51E2GPR84FFAR1SMN1; SMN2TET2 | |
| SCHEMBL264859 | 0.94 | — | — | |
| SCHEMBL193026 | 0.94 | — | — | |
| SCHEMBL6963 | 0.94 | — | — | |
| Acetic Acid SCHEMBL15322885 | 0.92 | OR51E2 (0.42) | OR51E2GPR84FFAR1SMN1; SMN2TET2 | |
| SCHEMBL11666742 | 0.91 | — | — | |
| Bicarbonate SCHEMBL21899730 | 0.91 | OR51E2 (0.50) | OR51E2GPR84FFAR1SMN1; SMN2TET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178698-B1 | A SYSTEM AND METHOD FOR MAKING, APPLYING AND REMOVING A TOP COATING FOR REMOVABLE GRAPHICS | CSD LLC (US) | 2016-03-23 | — | — | EP | disclosed |
| CN-101260373-B | Micrococcus luteus with novel metabolic characteristic and application thereof in biological degradation | UNIV DALIAN TECH | 2011-02-02 | — | — | CN | disclosed |
| US-20110011529-A1 | Removable adhesive for adhering an image to a surface and a method for removing the image | WARREN DONALD C | 2011-01-20 | — | — | US | disclosed |
| WO-2007059102-A3 | A REMOVABLE ADHESIVE FOR ADHERING AN IMAGE TO A SURFACE AND A METHOD FOR REMOVING THE IMAGE | WARREN DONALD (US) | 2007-09-07 | — | — | WO | disclosed |
| WO-2007059059-A2 | A REMOVABLE SOLVENT BASED PAINT FORMULATION AND SYSTEM | WARREN DONALD (US) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007059102-A2 | A REMOVABLE ADHESIVE FOR ADHERING AN IMAGE TO A SURFACE AND A METHOD FOR REMOVING THE IMAGE | WARREN DONALD (US) | 2007-05-24 | — | — | WO | disclosed |
| US-20070107636-A1 | Removable solvent based paint formulation and system | WARREN DONALD | 2007-05-17 | — | — | US | disclosed |
| US-20070110966-A1 | Removable adhesive for adhering an image to a surface and a method for removing the image | WARREN DONALD | 2007-05-17 | — | — | US | disclosed |
| CN-1245404-C | Mercaptoacetylamide derivatives, process for their preparation and use thereof | AVENTIS PHARMA GMBH (DE) | 2006-03-15 | — | — | CN | disclosed |
| CN-1501926-A | Mercaptoacetylamide derivatives, process for preparing the same and use thereof | ������ҽҩ�¹�����˾ | 2004-06-02 | — | — | CN | disclosed |
| US-5436279-A | Coating materials containing a reaction product of an epoxy novolak resin and an olefinically unsaturated carboxylic acid crosslinkable by radiation | RUTGERSWERKE AKTINGESELLSCHAFT (DE) | 1995-07-25 | — | — | US | disclosed |
| US-4544623-A | Photosensitive coating composition and the use thereof for protective purposes | CIBA-GEIGY CORPORATION (US) | 1985-10-01 | — | — | US | disclosed |