Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 9/20 | 0.44 |
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | MMP3 | P08254 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16370367 | 1.00 | CSNK1E (0.58) | CSNK1ESIGMAR1SLC6A2TAAR1MAOA | |
| SCHEMBL16752543 | 1.00 | CSNK1E (0.58) | CSNK1ESIGMAR1SLC6A2TAAR1MAOA | |
| SCHEMBL16752541 | 1.00 | CSNK1E (0.58) | CSNK1ESIGMAR1SLC6A2TAAR1MAOA | |
| SCHEMBL5678132 | 1.00 | CSNK1E (0.58) | CSNK1ESIGMAR1SLC6A2TAAR1MAOA | |
| SCHEMBL25212657 | 1.00 | CSNK1E (0.58) | CSNK1ESIGMAR1SLC6A2TAAR1MAOA | |
| SCHEMBL25204172 | 1.00 | CSNK1E (0.58) | CSNK1ESIGMAR1SLC6A2TAAR1MAOA | |
| SCHEMBL6060574 | 1.00 | CSNK1E (0.58) | CSNK1ESIGMAR1SLC6A2TAAR1MAOA | |
| SCHEMBL16752540 | 1.00 | CSNK1E (0.58) | CSNK1ESIGMAR1SLC6A2TAAR1MAOA | |
| Hydrogen Peroxide SCHEMBL27282969 | 0.98 | CSNK1E (0.61) | CSNK1ESIGMAR1CNR2MMP2MMP1 | |
| SCHEMBL6693090 | 0.98 | CSNK1E (0.56) | CSNK1ESIGMAR1SLC6A2TAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663918-A1 | PURE ENANTIOMERS OF PHOSPHORIC-ACID ESTERS AS PHOSPHOLIPASE-A2 INHIBITORS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994009014-A1 | PURE ENANTIOMERS OF PHOSPHORIC-ACID ESTERS AS PHOSPHOLIPASE-A2 INHIBITORS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1994-04-28 | — | — | WO | disclosed |