SCHEMBL9242572 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	GRM2	Q14416	15/20	0.51

▸	KDM4E	B2RXH2	1/20	0.40

▸	ALDH1A1	P00352	1/20	0.40

▸	LMNA	P02545	1/20	0.40

▸	HPGD	P15428	1/20	0.40

▸	TSHR	P16473	1/20	0.40

▸	ALOX12	P18054	1/20	0.40

▸	HTT	P42858	1/20	0.40

▸	SMN1; SMN2	Q16637	1/20	0.40

▸	GRM5	P41594	3/20	0.39

▸	MAPK1	P28482	1/20	0.39

▸	L3MBTL1	Q9Y468	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6801533	0.87	GRM2 (0.56)	GRM2
SCHEMBL8941939	0.84	GRM2 (0.57)	GRM2
SCHEMBL8942117	0.83	GRM2 (0.56)	GRM2
SCHEMBL9236212	0.82	GRM2 (0.60)	GRM2
SCHEMBL8941844	0.82	GRM2 (0.57)	GRM2
SCHEMBL2789355	0.81	GRM2 (0.60)	GRM2
SCHEMBL2786197	0.80	GRM2 (0.55)	GRM2
SCHEMBL8941850	0.80	GRM2 (0.55)	GRM2
SCHEMBL8942024	0.80	GRM2 (0.53)	GRM2
SCHEMBL2786765	0.80	GRM2 (0.49)	GRM2MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0645387-A1	THIAZOLIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME	TAIHO PHARMACEUTICAL CO., LTD. (JP)	1995-03-29	—	—	EP	disclosed