Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9243149 | 1.00 | FFAR1 (0.39) | FFAR1PAX8FFAR4GRIN2BDRD2 | |
| SCHEMBL9246498 | 0.86 | FFAR1 (0.36) | FFAR1PAX8FFAR4DRD2HTR2A | |
| SCHEMBL9246491 | 0.86 | FFAR1 (0.36) | FFAR1PAX8FFAR4DRD2HTR2A | |
| SCHEMBL9241173 | 0.85 | GRM2 (0.36) | FFAR1PAX8FFAR4DRD2HTR2A | |
| SCHEMBL9241181 | 0.85 | GRM2 (0.36) | FFAR1PAX8FFAR4DRD2HTR2A | |
| SCHEMBL9249112 | 0.84 | GRM2 (0.38) | FFAR1PAX8FFAR4DRD2HTR2A | |
| SCHEMBL9247430 | 0.84 | GRM2 (0.38) | FFAR1PAX8FFAR4DRD2HTR2A | |
| SCHEMBL9247434 | 0.84 | GRM2 (0.38) | FFAR1PAX8FFAR4DRD2HTR2A | |
| SCHEMBL9249104 | 0.84 | GRM2 (0.38) | FFAR1PAX8FFAR4DRD2HTR2A | |
| SCHEMBL9246011 | 0.83 | FFAR1 (0.38) | FFAR1PAX8FFAR4GRIN2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447657-A | Liquid crystal compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-09-05 | — | — | US | disclosed |