⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126671 | 0.77 | — | — | |
| SCHEMBL21737680 | 0.74 | — | — | |
| SCHEMBL20844121 | 0.72 | — | — | |
| SCHEMBL27845754 | 0.72 | — | — | |
| SCHEMBL20844143 | 0.72 | — | — | |
| SCHEMBL10962770 | 0.72 | — | — | |
| SCHEMBL17522837 | 0.72 | — | — | |
| SCHEMBL12732019 | 0.69 | DYRK1A (0.33) | — | |
| SCHEMBL20844107 | 0.69 | — | — | |
| SCHEMBL3465033 | 0.69 | DYRK1A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4103553-A1 | NEW PROCESS FOR THE SYNTHESIS OF 5-FLUORO-3- (DIFUOROMETHYL) -5-FLUORO-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES AND THE FREE ACID THEREOF | Fujian Yongjing Technology Co., Ltd (CN) | 2022-12-21 | — | — | EP | claimed |
| US-20220372000-A1 | New Process for the Synthesis of 5-Fluoro-3-(Difuoromethyl)-5-Fluoro-1-Methyl-1H-Pyrazole-4-Carboxylic Acid Derivatives and the Free Acid Thereof | Fujian Yongjing Technology Co.,Ltd (CN) | 2022-11-24 | — | — | US | claimed |
| CN-114450269-A | Novel method for synthesizing 5-fluoro-3- (difluoromethyl) -5-fluoro-1-methyl-1H-pyrazole-4-carboxylic acid derivative and free acid thereof | 福建永晶科技股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-120081788-A | Pyrazole amide compound containing 2- (4-bromo-2- (trifluoromethyl) phenoxy) phenyl fragment and application thereof | 安徽理工大学 | 2025-06-03 | — | — | CN | disclosed |
| CN-120091815-A | T-type voltage-gated calcium channel enhancer | 广泛研究所股份有限公司 | 2025-06-03 | — | — | CN | disclosed |
| US-12202826-B2 | N-pyridinyl acetamide derivatives as inhibitors of the Wnt signaling pathway | REDX PHARMA PLC (GB) | 2025-01-21 | — | — | US | disclosed |
| US-12180226-B2 | Spirotricycle RIPK1 inhibitors and methods of uses thereof | MERCK SHARP & DOHME LLC (US) | 2024-12-31 | — | — | US | disclosed |
| CN-116535357-B | Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application | 西北农林科技大学 | 2024-10-11 | — | — | CN | disclosed |
| EP-4423096-A1 | SPIROTRICYCLE RIPK1 INHIBITORS AND METHODS OF USES THEREOF | Merck Sharp & Dohme LLC (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-118488957-A | Spirotricyclic RIPK1 inhibitors and methods of use thereof | 默沙东有限责任公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-117534616-B | Synthesis method of 3-difluoromethyl-1, 5-disubstituted pyrazole compound | 西北师范大学 | 2024-07-30 | — | — | CN | disclosed |
| WO-2012163905-A1 | METHOD FOR PREPARING A FLUORINATED ORGANIC COMPOUND | RHODIA OPERATIONS (FR) | 2012-12-06 | — | — | WO | disclosed |
| EP-2215096-B1 | COPPER-OXYGEN ADDUCT COMPLEXES | UNIV GIESSEN JUSTUS LIEBIG (DE) | 2012-09-19 | — | — | EP | disclosed |
| US-20120016127-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20120016127-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) | 2012-01-19 | — | — | US | disclosed |
| US-7875647-B2 | and inverse agonist; 2-(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl)-5-(pyridin-4-yl)-1,3,4-oxadiazole; obesity and obesity-related metabolic disorders | GREEN CROSS CORPORATION (KR) | 2011-01-25 | — | — | US | disclosed |
| EP-2097410-A1 | HETEROARYL-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS | Green Cross Corporation (KR) | 2009-09-09 | — | — | EP | disclosed |
| WO-2009052809-A1 | COPPER-OXYGEN ADDUCT COMPLEXES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2009-04-30 | — | — | WO | disclosed |
| US-20080081812-A1 | Heteroaryl-Pyrazole Derivatives as Cannabinoid CB1 Receptor Antagonists | GREEN CROSS CORPORATION (KR) | 2008-04-03 | — | — | US | disclosed |
| WO-2008039023-A1 | HETEROARYL-PYRAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS | GREEN CROSS CORPORATION (KR) | 2008-04-03 | — | — | WO | disclosed |