SCHEMBL9243244

SCHEMBL9243244

CCCCCCOC(=O)C=CC(=O)OOOC(C)(C)C

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.59
ATM Q13315 1/20 0.56
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
APP P05067 4/20 0.43
TSHR P16473 3/20 0.42
NAAA Q02083 1/20 0.42
HTT P42858 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
EPHX1 P07099 1/20 0.40
PRKCA P17252 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9240635 1.00 HCAR2 (0.59) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9243239 1.00 HCAR2 (0.59) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9240625 1.00 HCAR2 (0.59) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9244689 1.00 HCAR2 (0.59) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9244681 1.00 HCAR2 (0.59) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9244457 1.00 HCAR2 (0.59) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9244445 1.00 HCAR2 (0.59) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9245719 0.98 HCAR2 (0.58) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9245726 0.98 HCAR2 (0.58) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL8892638 0.94 ATM (0.65) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434362-B1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution TOMEI SANGYO KK (JP) 1995-03-22 EP disclosed
EP-0433046-B1 Polymer-type polymerization initiator TOMEI SANGYO KK (JP) 1994-08-10 EP disclosed
US-5206298-A GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE TOMEI SANGYO KABUSHIKI KAISHA (JP) 1993-04-27 US disclosed
US-5134213-A N-Vinyllactam-Monoperoxyfumarate Terpolymer TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-07-28 US disclosed
US-5082912-A For graft polymerization, surfactants TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-01-21 US disclosed
EP-0434362-A1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-26 EP disclosed
EP-0433046-A2 Polymer-type polymerization initiator Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-19 EP disclosed