⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL28800527 | 0.87 | — | — | |
| Formic Acid SCHEMBL28896728 | 0.87 | — | — | |
| Carbamic Acid SCHEMBL29168073 | 0.85 | — | — | |
| SCHEMBL29052416 | 0.80 | — | — | |
| SCHEMBL28476861 | 0.78 | TSHR (0.38) | — | |
| Ethoxycarbonyl Group SCHEMBL28896756 | 0.78 | — | — | |
| SCHEMBL1024090 | 0.78 | — | — | |
| SCHEMBL30511359 | 0.75 | — | — | |
| SCHEMBL28218119 | 0.75 | — | — | |
| SCHEMBL3323215 | 0.75 | SMARCA2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112119063-B | Method for producing 3-difluoromethylpyrazole compound, method for producing 3-difluoromethylpyrazole-4-carboxylic acid compound, and pyrazolidine compound | 富士胶片株式会社 | 2023-10-17 | — | — | CN | claimed |
| EP-4103553-A1 | NEW PROCESS FOR THE SYNTHESIS OF 5-FLUORO-3- (DIFUOROMETHYL) -5-FLUORO-1-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES AND THE FREE ACID THEREOF | Fujian Yongjing Technology Co., Ltd (CN) | 2022-12-21 | — | — | EP | claimed |
| US-20220372000-A1 | New Process for the Synthesis of 5-Fluoro-3-(Difuoromethyl)-5-Fluoro-1-Methyl-1H-Pyrazole-4-Carboxylic Acid Derivatives and the Free Acid Thereof | Fujian Yongjing Technology Co.,Ltd (CN) | 2022-11-24 | — | — | US | claimed |
| CN-114450269-A | Novel method for synthesizing 5-fluoro-3- (difluoromethyl) -5-fluoro-1-methyl-1H-pyrazole-4-carboxylic acid derivative and free acid thereof | 福建永晶科技股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| US-11149010-B2 | Producing method for 3-difluoromethylpyrazole compound, producing method for 3-difluoromethylpyrazole-4-carboxylic acid compound, and pyrazolidine compound | FUJIFILM CORPORATION (JP) | 2021-10-19 | — | — | US | claimed |
| CN-113330001-A | 3, 3-difluoroallylamine or salt thereof and pharmaceutical composition containing same | 柳韩洋行 | 2021-08-31 | — | — | CN | claimed |
| US-20210061766-A1 | PRODUCING METHOD FOR 3-DIFLUOROMETHYLPYRAZOLE COMPOUND, PRODUCING METHOD FOR 3-DIFLUOROMETHYLPYRAZOLE-4-CARBOXYLIC ACID COMPOUND, AND PYRAZOLIDINE COMPOUND | FUJIFILM CORPORATION (JP) | 2021-03-04 | — | — | US | claimed |
| CN-112119063-A | Method for producing 3-difluoromethylpyrazole compound, method for producing 3-difluoromethylpyrazole-4-carboxylic acid compound, and pyrazolidine compound | 富士胶片株式会社 | 2020-12-22 | — | — | CN | claimed |
| CN-107427001-A | Fungicidal active substance combinations | 拜耳作物科学股份公司 | 2017-12-01 | — | — | CN | claimed |
| CN-103180317-B | Heteroarylpiperidine and piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-23 | — | — | CN | claimed |
| CN-102781937-B | As two (difluoromethyl) pyrazoles of sterilant | BAYER CROPSCIENCE AG (DE) | 2015-09-30 | — | — | CN | claimed |
| CN-104011032-A | Heteroarylpiperidine and piperazine derivatives as fungicides | BAYER IP GMBH | 2014-08-27 | — | — | CN | claimed |
| CN-103351339-A | 3-fluorinated alkyl-1-substituted pyrazole-4-carboxylic acid and preparation method thereof | ABA CHEMICALS CORP | 2013-10-16 | — | — | CN | claimed |
| CN-103180317-A | Heteroarylpiperidine and piperazine derivatives as fungicides | BAYER IP GMBH | 2013-06-26 | — | — | CN | claimed |
| CN-103003272-A | Bis (difluoromethyl) pyrazoles as fungicides | BAYER CROPSCIENCE AG | 2013-03-27 | — | — | CN | claimed |
| CN-102781937-A | Bis(difluormethyl)pyrazoles used as fungicides | BAYER CROPSCIENCE AG | 2012-11-14 | — | — | CN | claimed |
| EP-4733303-A1 | MUSCARINIC M4 RECEPTOR AGONIST AND USE THEREOF | Haisco Pharmaceutical Group Co., Ltd. (CN) | 2026-04-29 | — | — | EP | disclosed |
| US-20260109696-A1 | SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS | Interdict Bio, Inc. (US) | 2026-04-23 | — | — | US | disclosed |
| EP-0731794-A1 | 1,4,5-TRIPHENYL PYRAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION AND INFLAMMATION-RELATED DISORDERS | SEARLE & CO (US) | 1996-09-18 | — | — | EP | disclosed |
| WO-1995015317-A1 | 1,4,5-TRIPHENYL PYRAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION AND INFLAMMATION-RELATED DISORDERS | G.D. SEARLE & CO. (US) | 1995-06-08 | — | — | WO | disclosed |