Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 4/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL8981847 | 0.98 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| Ethylene Glycol SCHEMBL27604937 | 0.87 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| Methyl Alcohol SCHEMBL28184611 | 0.87 | — | — | |
| SCHEMBL28606958 | 0.87 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL36144 | 0.87 | — | — | |
| Ether SCHEMBL273352 | 0.86 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Chloromethane SCHEMBL27637435 | 0.84 | — | — | |
| Lithium SCHEMBL31392601 | 0.84 | — | — | |
| SCHEMBL4629752 | 0.84 | — | — | |
| Ethylene SCHEMBL247222 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101552327-A | Preparing of composite polymer modified diaphragm containing shape selectivity molecular sieve filling agent | UNIV HUNAN (CN) | 2009-10-07 | — | — | CN | claimed |
| US-5458877-A | Artificial soil | TAKEDA GARDEN PRODUCTS CO., LTD. (JP) | 1995-10-17 | — | — | US | claimed |
| EP-0568955-A1 | Ink jet dyeing method for preheated textile | YKK CORPORATION (JP) | 1993-11-10 | — | — | EP | claimed |
| JP-58209983-A | — | — | None | — | — | JP | disclosed |
| US-5458877-A | Artificial soil | TAKEDA GARDEN PRODUCTS CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |
| EP-0409186-B1 | Artificial bed soil | TAKEDA GARDEN PROD (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5268105-A | Method for dehydrating human-waste disposal materials | KOHTOKU INDUSTRIAL WASTE MANAGEMENT INCORPORATION (JP) | 1993-12-07 | — | — | US | disclosed |
| EP-0568955-A1 | Ink jet dyeing method for preheated textile | YKK CORPORATION (JP) | 1993-11-10 | — | — | EP | disclosed |
| EP-0409186-A2 | Artificial bed soil | TAKEDA GARDEN PRODUCTS CO., LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |
| JP-S58209983-A | PREPARATION OF IMMOBILIZED ENZYME | MATSUSHITA ELECTRIC WORKS LTD | 1983-12-07 | — | — | JP | disclosed |