Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585914 | 0.85 | — | — | |
| SCHEMBL4364980 | 0.84 | — | — | |
| SCHEMBL4779628 | 0.73 | — | — | |
| SCHEMBL23071323 | 0.66 | — | — | |
| SCHEMBL433316 | 0.66 | MEN1 (0.40) | MEN1ALDH1A1POLBKMT2A | |
| SCHEMBL7191657 | 0.63 | — | — | |
| Pyridine SCHEMBL361440 | 0.61 | TDP1 (0.50) | — | |
| SCHEMBL11212390 | 0.61 | — | — | |
| SCHEMBL9797526 | 0.60 | MEN1 (0.30) | MEN1ALDH1A1POLBKMT2A | |
| SCHEMBL171443 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395931-A | 6-amido-1-methyl-2-(substituted-thio)carbapenems | MERCK & CO., INC. (US) | 1995-03-07 | — | — | US | disclosed |
| EP-0350210-A2 | Novel 6-amido-1-methyl-2-(substituted-thio)-carbapenems | MERCK & CO. INC. (US) | 1990-01-10 | — | — | EP | disclosed |