SCHEMBL9245014

SCHEMBL9245014

CCOC(=O)C=CC(=O)OC(CC)[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.44
ATM Q13315 1/20 0.37
MAPT P10636 8/20 0.35
LMNA P02545 3/20 0.33
MDM2 Q00987 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
MDM4 O15151 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALDH1A1 P00352 2/20 0.32
TTR P02766 1/20 0.31
DPP4 P27487 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9244973 1.00 HCAR2 (0.44) HCAR2ATMMAPTLMNAMDM2
SCHEMBL8853811 0.92 HCAR2 (0.34) HCAR2ATM
SCHEMBL7179281 0.92 HCAR2 (0.34) HCAR2ATM
SCHEMBL9243681 0.88 HCAR2 (0.44) HCAR2ATMMAPTLMNAMDM2
SCHEMBL9243494 0.88 HCAR2 (0.44) HCAR2ATMMAPTLMNAMDM2
SCHEMBL7179299 0.86 HCAR2 (0.46) HCAR2ATM
SCHEMBL9244881 0.86 HCAR2 (0.46) HCAR2ATMCA12CA1CA2
SCHEMBL9244908 0.86 HCAR2 (0.46) HCAR2ATMCA12CA1CA2
SCHEMBL9242302 0.86 HCAR2 (0.42) HCAR2ATM
SCHEMBL8733179 0.86 HCAR2 (0.31) HCAR2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434362-B1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution TOMEI SANGYO KK (JP) 1995-03-22 EP disclosed
EP-0433046-B1 Polymer-type polymerization initiator TOMEI SANGYO KK (JP) 1994-08-10 EP disclosed
US-5206298-A GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE TOMEI SANGYO KABUSHIKI KAISHA (JP) 1993-04-27 US disclosed
US-5134213-A N-Vinyllactam-Monoperoxyfumarate Terpolymer TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-07-28 US disclosed
US-5082912-A For graft polymerization, surfactants TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-01-21 US disclosed
EP-0434362-A1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-26 EP disclosed
EP-0433046-A2 Polymer-type polymerization initiator Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-19 EP disclosed