SCHEMBL9245490

SCHEMBL9245490

N#Cc1ccc(S(=O)(=O)NF)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.58
IDO1 P14902 3/20 0.53
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
KDM1A O60341 1/20 0.49
HSD11B1 P28845 3/20 0.46
KMT2A Q03164 1/20 0.46
KDM4E B2RXH2 1/20 0.46
MMP1 P03956 2/20 0.45
MMP2 P08253 2/20 0.45
MMP3 P08254 2/20 0.45
MMP7 P09237 2/20 0.45
MMP9 P14780 2/20 0.45
MMP13 P45452 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13590961 0.83 CYP19A1 (0.61) CYP19A1IDO1CA1CA2CA12
SCHEMBL19787562 0.81 CYP19A1 (0.59) CYP19A1IDO1CA1CA2CA12
SCHEMBL20256301 0.79 CYP19A1 (0.58) CYP19A1IDO1CA1CA2CA12
SCHEMBL2495472 0.79 CYP19A1 (0.58) CYP19A1IDO1CA1CA2CA12
SCHEMBL422400 0.79 CYP19A1 (0.58) CYP19A1IDO1CA1CA2CA12
SCHEMBL4613144 0.79 CYP19A1 (0.58) CYP19A1IDO1CA1CA2CA12
SCHEMBL5333725 0.78 CYP19A1 (0.56) CYP19A1IDO1CA1CA2CA12
SCHEMBL21800158 0.78 CYP19A1 (0.56) CYP19A1IDO1CA1CA2CA12
SCHEMBL5333727 0.76 CYP19A1 (0.54) CYP19A1IDO1CA1CA2CA12
SCHEMBL13623391 0.76 CYP19A1 (0.54) CYP19A1IDO1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5403957-A Method for preparing N-fluorosulfonimides ALLIEDSIGNAL INC. 1995-04-04 US claimed
US-5478964-A N-fluorosulfonimides and their application as fluorinating agents ALLIED-SIGNAL INC. (US) 1995-12-26 US disclosed
US-5254732-A N-fluorosulfonimides and their application as fluorinating agents ALLIED-SIGNAL INC. (US) 1993-10-19 US disclosed