Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197946 | 0.84 | KMT2A (1.00) | KMT2AALDH1A1MEN1KDM4ECRHBP | |
| SCHEMBL19607880 | 0.76 | KMT2A (0.72) | KMT2AALDH1A1MAPTHTTPDE4B | |
| SCHEMBL8023568 | 0.76 | KMT2A (0.72) | KMT2AALDH1A1PDE4BPDE3A | |
| SCHEMBL7008510 | 0.73 | MAPT (0.71) | KMT2AALDH1A1MEN1KDM4EHPGD | |
| SCHEMBL16319198 | 0.72 | KMT2A (0.76) | KMT2AALDH1A1MEN1CRHBPCRHR2 | |
| SCHEMBL16319317 | 0.72 | KMT2A (0.76) | KMT2AALDH1A1MEN1L3MBTL1MAPT | |
| SCHEMBL28606256 | 0.72 | KMT2A (0.76) | KMT2AALDH1A1MEN1KDM4EPKM | |
| SCHEMBL13936247 | 0.71 | KMT2A (0.62) | KMT2AALDH1A1MEN1KDM4EHPGD | |
| SCHEMBL8051164 | 0.71 | KMT2A (0.62) | KMT2AALDH1A1MEN1KDM4EPKM | |
| SCHEMBL13317551 | 0.71 | MAPT (0.76) | KMT2AALDH1A1MEN1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414108-A | From a Meldrum's acid derivative | BIOGAL GYOGYSZERGRAR (HU) | 1995-05-09 | — | — | US | disclosed |
| US-5350872-A | Decyclization and decarboxylation of a 1,3-dioxane-4,6-dione | BIOGAL GYOGYSZERGRAR (HU) | 1994-09-27 | — | — | US | disclosed |
| EP-0578850-A1 | Process for the preparation of carboxylic acids and derivatives of them | BIOGAL GYOGYSZERGYAR (HU) | 1994-01-19 | — | — | EP | disclosed |