Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244642 | 0.91 | GAA (0.56) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL10717601 | 0.84 | CYP3A4 (0.41) | ALDH1A1MAPTPOLBKDM4ETSHR | |
| Chloroneb SCHEMBL22739 | 0.84 | GAA (0.64) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL1098582 | 0.80 | NPC1 (0.45) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL30487990 | 0.79 | GAA (0.65) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL27952777 | 0.79 | GAA (0.65) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL5181298 | 0.79 | CYP3A4 (0.43) | GAAALDH1A1MAPTKDM4ETSHR | |
| SCHEMBL3757554 | 0.79 | NPC1 (0.65) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL16609990 | 0.76 | GAA (0.68) | GAANPC1TAAR1ALDH1A1MAPT | |
| SCHEMBL10356771 | 0.75 | GAA (0.54) | GAANPC1TAAR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437186-B1 | Melamine derivatives as stabilizers for chlorine containing polymers | CIBA GEIGY AG (CH) | 1995-12-06 | — | — | EP | disclosed |
| EP-0365483-B1 | Mercaptobenzoic-acid esters used as stabilizers for chlorine-containing polymers | CIBA GEIGY AG (CH) | 1993-12-29 | — | — | EP | disclosed |
| US-5272192-A | Melamine derivatives as stabilizers for chloride-containing polymers | CIBA-GEIGY CORPORATION (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0437186-A1 | Melamine derivatives as stabilizers for chlorine containing polymers | CIBA-GEIGY AG (CH) | 1991-07-17 | — | — | EP | disclosed |
| US-5030671-A | Metal carboxylate and/or phenolate mixture | CIBA-GEIGY CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0365483-A1 | Mercaptobenzoic-acid esters used as stabilizers for chlorine-containing polymers | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | disclosed |