Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246803 | 1.00 | GAA (0.33) | GAAMAPTGRM2MEN1KMT2A | |
| SCHEMBL9250750 | 0.96 | GAA (0.32) | GAAMAPTGRM2MEN1KMT2A | |
| SCHEMBL9250755 | 0.96 | GAA (0.32) | GAAMAPTGRM2MEN1KMT2A | |
| SCHEMBL9251351 | 0.87 | MEN1 (0.39) | GAAMAPTGRM2MEN1KMT2A | |
| SCHEMBL9251341 | 0.87 | MEN1 (0.39) | GAAMAPTGRM2MEN1KMT2A | |
| SCHEMBL9249839 | 0.85 | SPHK1 (0.42) | GAAMAPTCYP2C9ITGB3ITGA2B | |
| SCHEMBL9249834 | 0.85 | SPHK1 (0.42) | GAAMAPTCYP2C9ITGB3ITGA2B | |
| SCHEMBL9242513 | 0.83 | MEN1 (0.37) | GAAMAPTGRM2MEN1KMT2A | |
| SCHEMBL9242502 | 0.83 | MEN1 (0.37) | GAAMAPTGRM2MEN1KMT2A | |
| SCHEMBL9244946 | 0.81 | OPRL1 (0.41) | GAAMAPTMEN1KMT2AOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995013257-A1 | 2,6-DIFLUOROBENZENES AND THEIR USE IN LIQUID-CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 1995-05-18 | — | — | WO | disclosed |