Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | SLC33A1 | O00400 | 14/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250049 | 1.00 | PPARG (0.41) | PPARGSLC33A1EGLN2KDM4EALDH1A1 | |
| SCHEMBL9250470 | 0.86 | SLC33A1 (0.45) | PPARGSLC33A1 | |
| SCHEMBL7311768 | 0.85 | PPARG (0.46) | PPARGSLC33A1 | |
| SCHEMBL9252860 | 0.85 | PPARG (0.44) | PPARGSLC33A1 | |
| SCHEMBL9253652 | 0.85 | PPARG (0.46) | PPARGSLC33A1 | |
| SCHEMBL9251529 | 0.85 | PPARG (0.44) | PPARGSLC33A1 | |
| SCHEMBL9250489 | 0.84 | PPARG (0.43) | PPARGSLC33A1 | |
| SCHEMBL9250140 | 0.83 | PPARG (0.45) | PPARGSLC33A1 | |
| SCHEMBL9254223 | 0.82 | PPARG (0.42) | PPARGSLC33A1 | |
| Diethylamine SCHEMBL9256272 | 0.82 | PPARG (0.44) | PPARGSLC33A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387747-A | Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis | LABORATOIRES UPSA (FR) | 1995-02-07 | — | — | US | disclosed |