Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.96 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.83 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.83 |
| ▸ | STS | P08842 | 3/20 | 0.81 |
| ▸ | LMNA | P02545 | 5/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.75 |
| ▸ | ESR1 | P03372 | 5/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | PGR | P06401 | 2/20 | 0.73 |
| ▸ | AR | P10275 | 2/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.73 |
| ▸ | ATM | Q13315 | 2/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4966962 | 0.98 | KDM4E (1.00) | KDM4EABCC4ABCC1STSLMNA | |
| SCHEMBL2291502 | 0.98 | KDM4E (1.00) | KDM4EABCC4ABCC1STSLMNA | |
| SCHEMBL232797 | 0.91 | ABCC4 (1.00) | KDM4EABCC4ABCC1STSLMNA | |
| SCHEMBL29392632 | 0.91 | ABCC4 (1.00) | KDM4EABCC4ABCC1STSLMNA | |
| SCHEMBL30471686 | 0.91 | ABCC4 (1.00) | KDM4EABCC4ABCC1STSLMNA | |
| SCHEMBL232796 | 0.91 | ABCC4 (1.00) | KDM4EABCC4ABCC1STSLMNA | |
| E2Mate SCHEMBL5165269 | 0.90 | STS (1.00) | KDM4EABCC4ABCC1STSLMNA | |
| SCHEMBL19121776 | 0.90 | ABCC4 (0.83) | KDM4EABCC4ABCC1STSLMNA | |
| E2Mate SCHEMBL5151234 | 0.90 | STS (1.00) | KDM4EABCC4ABCC1STSLMNA | |
| SCHEMBL21033841 | 0.90 | ABCC4 (0.83) | KDM4EABCC4ABCC1STSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393529-A | Sustained release | LTS LOHMANN THERAPIE-SYSTEME GMBH & CO. KG (DE) | 1995-02-28 | — | — | US | disclosed |