SCHEMBL9248652

SCHEMBL9248652

C=CC(=O)OC=C(C)C(=O)OCCC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.46
HPGD P15428 1/20 0.46
HCAR2 Q8TDS4 1/20 0.38
ALDH1A1 P00352 6/20 0.37
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 2/20 0.37
HSD17B10 Q99714 1/20 0.37
THRB P10828 4/20 0.36
ATM Q13315 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
MAPK1 P28482 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23674606 0.90 TSHR (0.61) TSHRHPGDHCAR2ALDH1A1TP53
SCHEMBL25185169 0.89 TSHR (0.54) TSHRHPGDHCAR2ALDH1A1CYP3A4
SCHEMBL22042871 0.87 TSHR (0.54) TSHRHPGDHCAR2ALDH1A1CYP3A4
SCHEMBL22572577 0.87 TSHR (0.54) TSHRHPGDHCAR2ALDH1A1CYP3A4
SCHEMBL22572644 0.87 TSHR (0.54) TSHRHPGDHCAR2ALDH1A1CYP3A4
SCHEMBL28788510 0.87 TSHR (0.54) TSHRHPGDHCAR2ALDH1A1CYP3A4
SCHEMBL25216801 0.87 TSHR (0.54) TSHRHPGDHCAR2ALDH1A1CYP3A4
SCHEMBL25426670 0.87 TSHR (0.54) TSHRHPGDHCAR2ALDH1A1CYP3A4
SCHEMBL28116365 0.87 TSHR (0.54) TSHRHPGDHCAR2ALDH1A1CYP3A4
SCHEMBL4805596 0.86 NPSR1 (0.41) TSHRHPGDHCAR2ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116368434-A Photosensitive resin composition, photosensitive material, black matrix and electronic element containing the same 株式会社LG化学 2023-06-30 CN disclosed
CN-111712523-B Ophthalmic product composition 爱尔兰眼力健公司 2023-01-03 CN disclosed
CN-111712523-A Ophthalmic product composition 默克专利股份有限公司 2020-09-25 CN disclosed
CN-106663739-B Solar cell and method for manufacturing same 株式会社LG化学 2019-08-30 CN disclosed
CN-107075761-A Method of making superabsorbent polymer fibers 株式会社LG化学 2017-08-18 CN disclosed
CN-106663739-A Solar cell and method for manufacturing same 株式会社LG化学 2017-05-10 CN disclosed
CN-104768925-B Styryl-based compound and use thereof in coloring material, photosensitive resin, resist material, color filter and display device 株式会社LG化学 2017-03-08 CN disclosed
CN-106188559-A Dispersant and preparation method thereof, CNT dispersion pulp and preparation method thereof 中山大桥化工集团有限公司 2016-12-07 CN disclosed
CN-104144797-B Tyre for vehicle wheels 株式会社普利司通 2016-06-22 CN disclosed
CN-104768925-A Styryl-based compound, coloring material comprising the styryl-based compound, photosensitive resin composition comprising the coloring material, photoresist material prepared from the photosensitive resin composition, color filter comprising the photoresist material, and display device comprising the color filter LG CHEMICAL LTD 2015-07-08 CN disclosed
CN-104144797-A Tyre for vehicle wheels BRIDGESTONE CORP 2014-11-12 CN disclosed
CN-1711326-A Ultraviolet-curable antistatic hard coat resin composition DENKI KAGAKU KOGYO KK (JP) 2005-12-21 CN disclosed
EP-0348565-B1 Polymers comprising alkali-insoluble core/alkali-soluble shell and compositions thereof ROHM & HAAS (US) 1995-03-22 EP disclosed
EP-0348565-A1 Polymers comprising alkali-insoluble core/alkali-soluble shell and compositions thereof ROHM AND HAAS COMPANY (US) 1990-01-03 EP disclosed