Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 4/20 | 0.42 |
| ▸ | JAK1 | P23458 | 4/20 | 0.42 |
| ▸ | TYK2 | P29597 | 4/20 | 0.42 |
| ▸ | JAK3 | P52333 | 4/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254928 | 0.98 | HDAC1 (0.47) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL9255124 | 0.89 | HDAC1 (0.50) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL9251150 | 0.87 | HDAC1 (0.50) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL9251773 | 0.87 | HDAC1 (0.50) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| Hydrochloric Acid SCHEMBL8863892 | 0.87 | HDAC1 (0.49) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| Hydrochloric Acid SCHEMBL9251702 | 0.85 | HDAC1 (0.45) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL8863519 | 0.85 | HDAC1 (0.52) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| Hydrochloric Acid SCHEMBL9255053 | 0.84 | HDAC1 (0.51) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL9256146 | 0.83 | HDAC1 (0.45) | HDAC1HDAC8HDAC6HDAC3HDAC2 | |
| SCHEMBL9251154 | 0.83 | NQO2 (0.48) | HDAC1HDAC8HDAC6HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |