SCHEMBL9249367 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	OPRL1	P41146	14/20	0.37

▸	CYP1A2	P05177	2/20	0.36

▸	MEN1	O00255	2/20	0.34

▸	GAA	P10253	2/20	0.34

▸	MAPK1	P28482	2/20	0.34

▸	KMT2A	Q03164	2/20	0.34

▸	NPC1	O15118	1/20	0.34

▸	CYP2D6	P10635	1/20	0.34

▸	MAPT	P10636	1/20	0.34

▸	CYP2C9	P11712	1/20	0.34

▸	HPGD	P15428	1/20	0.34

▸	TSHR	P16473	1/20	0.34

▸	CYP2C19	P33261	1/20	0.34

▸	RAB9A	P51151	1/20	0.34

▸	SMN1; SMN2	Q16637	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9249377	1.00	OPRL1 (0.37)	OPRL1CYP1A2MEN1GAAMAPK1
SCHEMBL9249400	0.96	GAA (0.37)	OPRL1MEN1GAAKMT2AMAPT
SCHEMBL9249405	0.96	GAA (0.37)	OPRL1MEN1GAAKMT2AMAPT
SCHEMBL9405739	0.96	OPRL1 (0.39)	OPRL1CYP1A2MEN1GAAMAPK1
SCHEMBL9405734	0.96	OPRL1 (0.39)	OPRL1CYP1A2MEN1GAAMAPK1
SCHEMBL14494545	0.91	OPRL1 (0.39)	OPRL1MEN1MAPK1KMT2AMAPT
SCHEMBL2905649	0.91	OPRL1 (0.39)	OPRL1MEN1MAPK1KMT2AMAPT
SCHEMBL2905645	0.91	OPRL1 (0.39)	OPRL1MEN1MAPK1KMT2AMAPT
SCHEMBL2905643	0.91	OPRL1 (0.39)	OPRL1MEN1MAPK1KMT2AMAPT
SCHEMBL9406020	0.91	GAA (0.39)	OPRL1CYP1A2MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1995010496-A1	2,3,4-TRIFLUOROBENZENES AND THEIR USE IN LIQUID CRYSTAL MIXTURES	MERCK PATENT GMBH (DE)	1995-04-20	—	—	WO	disclosed