SCHEMBL9249694

SCHEMBL9249694

CC(=O)/C(F)=C/CCCCCCCOc1ccc2ccccc2n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CYSLTR2 Q9NS75 5/20 0.38
CYSLTR1 Q9Y271 5/20 0.38
LTB4R Q15722 6/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
HTT P42858 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9249698 1.00 MAPT (0.43) MAPTMEN1KMT2ACYSLTR2CYSLTR1
SCHEMBL9249700 1.00 MAPT (0.43) MAPTMEN1KMT2ACYSLTR2CYSLTR1
SCHEMBL9245638 0.86 CYSLTR2 (0.43) MAPTMEN1KMT2ACYSLTR2CYSLTR1
SCHEMBL9247507 0.86 CYSLTR2 (0.43) MAPTMEN1KMT2ACYSLTR2CYSLTR1
SCHEMBL9245633 0.86 CYSLTR2 (0.43) MAPTMEN1KMT2ACYSLTR2CYSLTR1
SCHEMBL9247512 0.86 CYSLTR2 (0.43) MAPTMEN1KMT2ACYSLTR2CYSLTR1
SCHEMBL9248748 0.85 CYSLTR2 (0.41) MAPTMEN1KMT2ACYSLTR2CYSLTR1
SCHEMBL9246999 0.85 MAPT (0.37) MAPTMEN1KMT2ACYSLTR2CYSLTR1
SCHEMBL9246997 0.85 MAPT (0.37) MAPTMEN1KMT2ACYSLTR2CYSLTR1
SCHEMBL9646718 0.84 MAPT (0.46) MAPTMEN1KMT2ACYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0346107-B1 Arylfluoroalkenamides and their use as pesticides ROUSSEL UCLAF (FR) 1995-09-13 EP disclosed
US-5114940-A Insecticides or anthelmintics from fused ring heterocycles containing amides or thioamides ROUSSEL-UCLAF (FR) 1992-05-19 US disclosed
EP-0346107-A2 Arylfluoroalkenamides and their use as pesticides ROUSSEL UCLAF (FR) 1989-12-13 EP disclosed