Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250246 | 1.00 | PTAFR (0.56) | PTAFRKDM4EALDH1A1HRH1KCNH2 | |
| SCHEMBL9278556 | 0.88 | PTAFR (0.47) | PTAFRKDM4EALDH1A1 | |
| SCHEMBL9257039 | 0.84 | PTAFR (0.56) | PTAFRKDM4EALDH1A1 | |
| SCHEMBL9257047 | 0.84 | PTAFR (0.56) | PTAFRKDM4EALDH1A1 | |
| SCHEMBL9668961 | 0.81 | PTAFR (0.57) | PTAFRKDM4EALDH1A1 | |
| SCHEMBL9669732 | 0.81 | PTAFR (0.59) | PTAFRKDM4EALDH1A1 | |
| SCHEMBL9669731 | 0.81 | PTAFR (0.59) | PTAFRKDM4EALDH1A1 | |
| SCHEMBL9257611 | 0.81 | PTAFR (0.57) | PTAFRKDM4EALDH1A1 | |
| SCHEMBL9257616 | 0.81 | PTAFR (0.57) | PTAFRKDM4EALDH1A1 | |
| SCHEMBL9258677 | 0.79 | PTAFR (0.59) | PTAFRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |