Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15253262 | 0.90 | HRH3 (0.49) | HRH3HPGDALDH1A1HTTKMT2A | |
| SCHEMBL15254857 | 0.89 | HRH3 (0.48) | HRH3HPGDALDH1A1HTTKMT2A | |
| SCHEMBL15253550 | 0.88 | HRH3 (0.48) | HRH3HPGDALDH1A1HTTKMT2A | |
| SCHEMBL15253351 | 0.88 | MEN1 (0.51) | HRH3HPGDALDH1A1HTTKMT2A | |
| SCHEMBL15253253 | 0.88 | MEN1 (0.52) | HRH3HPGDALDH1A1HTTKMT2A | |
| SCHEMBL15253304 | 0.88 | MEN1 (0.55) | HRH3HPGDALDH1A1HTTKMT2A | |
| SCHEMBL15253539 | 0.88 | HRH3 (0.47) | HRH3HPGDALDH1A1HTTKMT2A | |
| SCHEMBL15253522 | 0.88 | HRH3 (0.47) | HRH3HPGDALDH1A1HTTKMT2A | |
| SCHEMBL8533305 | 0.88 | HRH3 (0.47) | HRH3HPGDALDH1A1HTTKMT2A | |
| SCHEMBL15253368 | 0.87 | KMT2A (0.56) | HRH3HPGDALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069917-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |