SCHEMBL9250878

SCHEMBL9250878

[CH]C#CCCCCCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.46
HMGCR P04035 3/20 0.46
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
SLC22A1 O15245 1/20 0.41
KCNH2 Q12809 1/20 0.39
ALDH1A1 P00352 2/20 0.39
ALOX12 P18054 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9250669 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL16527612 1.00 PTPN7 (0.46) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL6184484 0.97
SCHEMBL6182727 0.88
SCHEMBL23040316 0.82 PTPN7 (0.61) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL11066113 0.82 PTPN7 (0.61) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL9211891 0.82 PTPN7 (0.61) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL1523678 0.82 PTPN7 (0.61) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL513302 0.82 PTPN7 (0.61) PTPN7HMGCRTSHRTHRBRECQL
SCHEMBL10796010 0.82 PTPN7 (0.61) PTPN7HMGCRTSHRTHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5384342-A Adhesion promoter in UV curable coating for glass DSM DESOTECH, INC. (US) 1995-01-24 US disclosed