SCHEMBL9251015

SCHEMBL9251015

COc1ccc2c(c1)C(=Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C(=O)N2OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EEF2K O00418 1/20 0.46
SRC P12931 1/20 0.46
EGFR P00533 2/20 0.45
LCK P06239 3/20 0.44
PRKACA P17612 1/20 0.44
PRKACG P22612 1/20 0.44
PRKACB P22694 1/20 0.44
ERBB2 P04626 1/20 0.43
IGF1R P08069 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
LRRK2 Q5S007 1/20 0.41
SIRT1 Q96EB6 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CTRC Q99895 1/20 0.40
PLK4 O00444 1/20 0.39
GAA P10253 2/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8539596 0.88 EEF2K (0.41) EEF2KSRCEGFRERBB2IGF1R
SCHEMBL8544169 0.88 EEF2K (0.47) EEF2KSRCEGFRERBB2IGF1R
SCHEMBL7312451 0.88 PLK4 (0.52) EEF2KSRCEGFRLCKPRKACA
SCHEMBL7312445 0.88 PLK4 (0.52) EEF2KSRCEGFRLCKPRKACA
SCHEMBL8544637 0.87 EEF2K (0.46) EEF2KSRCEGFRERBB2IGF1R
SCHEMBL8539973 0.85 EGFR (0.44) EEF2KSRCEGFRERBB2IGF1R
SCHEMBL8544253 0.85 ERBB2 (0.54) EEF2KSRCEGFRERBB2IGF1R
SCHEMBL8545505 0.85 EEF2K (0.44) EEF2KSRCEGFRERBB2IGF1R
SCHEMBL8544618 0.84 EEF2K (0.48) EEF2KSRCEGFRLCKERBB2
SCHEMBL8539727 0.83 EEF2K (0.49) EEF2KSRCEGFRERBB2IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5382593-A Antioxidants or anticoagulants ADIR ET COMPAGNIE (FR) 1995-01-17 US disclosed