Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254957 | 0.90 | NAMPT (0.51) | NAMPTDHFR | |
| SCHEMBL9246347 | 0.89 | NAMPT (0.54) | NAMPTDHFR | |
| SCHEMBL9298837 | 0.89 | NAMPT (0.43) | NAMPT | |
| SCHEMBL9388293 | 0.89 | NAMPT (0.45) | NAMPT | |
| SCHEMBL9299316 | 0.88 | TYMS (0.43) | NAMPT | |
| SCHEMBL8490827 | 0.86 | NAMPT (0.51) | NAMPT | |
| SCHEMBL9255397 | 0.85 | NAMPT (0.65) | NAMPT | |
| SCHEMBL8489069 | 0.83 | TYMS (0.40) | NAMPT | |
| SCHEMBL8485192 | 0.82 | — | — | |
| SCHEMBL8488020 | 0.81 | NAMPT (0.34) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395838-A | Aromatic aminomethyl substitutes compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-03-07 | — | — | US | disclosed |
| US-5280027-A | Quinazoline containing compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-18 | — | — | US | disclosed |
| US-5252573-A | Quinazoline derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-12 | — | — | US | disclosed |
| US-5089499-A | Anticarcinogenic agents; thymidylate synthetase inhibitors; antiallergens; psoriasis | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-18 | — | — | US | disclosed |