Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5301722 | 0.83 | TSHR (0.43) | TSHRFAAHTRPV1MEN1TP53 | |
| SCHEMBL2571771 | 0.73 | TSHR (0.79) | TSHRFAAHTRPV1CYP1A2CYP2C19 | |
| SCHEMBL30861 | 0.72 | — | — | |
| SCHEMBL6063283 | 0.71 | TSHR (0.84) | TSHRFAAHTRPV1CYP1A2CYP2C19 | |
| SCHEMBL25178868 | 0.71 | TSHR (0.84) | TSHRFAAHTRPV1CYP1A2CYP2C19 | |
| SCHEMBL25178165 | 0.71 | TSHR (0.84) | TSHRFAAHTRPV1CYP1A2CYP2C19 | |
| SCHEMBL8401773 | 0.71 | TSHR (0.84) | TSHRFAAHTRPV1CYP1A2CYP2C19 | |
| SCHEMBL20543170 | 0.71 | TSHR (0.84) | TSHRFAAHTRPV1CYP1A2CYP2C19 | |
| SCHEMBL20543165 | 0.71 | TSHR (0.84) | TSHRFAAHTRPV1CYP1A2CYP2C19 | |
| SCHEMBL1255937 | 0.71 | TSHR (0.84) | TSHRFAAHTRPV1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402729-B1 | Polycarbonates having vinylaromatic endgroup | BAYER AG (DE) | 1995-03-01 | — | — | EP | disclosed |
| EP-0348744-A3 | TRIALKYLSILYLOXY-1,1-DISPHENYL-ETHYLENES AND POLYMERS PREPARED THEREWITH | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0402729-A2 | Polycarbonates having vinylaromatic endgroup | BAYER AG (DE) | 1990-12-19 | — | — | EP | disclosed |
| EP-0348744-A2 | Trialkylsilyloxy-1,1-disphenyl-ethylenes and polymers prepared therewith | BAYER AG (DE) | 1990-01-03 | — | — | EP | disclosed |
| EP-0348744-A2 | Trialkylsilyloxy-1,1-disphenyl-ethylenes and polymers prepared therewith | BAYER AG (DE) | 1990-01-03 | — | — | EP | disclosed |