Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9249587 | 0.99 | CYP2C19 (0.59) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL9821357 | 0.92 | CYP2C19 (0.62) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL9256748 | 0.90 | CYP2C19 (0.49) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9255254 | 0.89 | CYP2C19 (0.48) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL9254016 | 0.89 | KDM4E (0.58) | CYP2C19ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL9252507 | 0.88 | CYP2C19 (0.46) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9254215 | 0.86 | KCNH2 (0.46) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL9819523 | 0.85 | CYP2C19 (0.56) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL9249850 | 0.85 | CYP2C19 (0.64) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 | |
| SCHEMBL28298203 | 0.83 | CHRM2 (0.79) | CYP2C19CHRM2OPRK1CYP1A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446146-A | Treatment of liver disorders | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0326379-B1 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5070089-A | INHIBITION OF LIPID PEROXIDATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0326379-A2 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |