⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5415178 | 0.77 | — | — | |
| SCHEMBL1512232 | 0.75 | — | — | |
| SCHEMBL536875 | 0.75 | — | — | |
| SCHEMBL5622392 | 0.75 | POLB (0.35) | — | |
| SCHEMBL7955145 | 0.71 | POLB (0.32) | — | |
| SCHEMBL17685 | 0.69 | — | — | |
| SCHEMBL25364773 | 0.69 | MAOB (0.41) | — | |
| SCHEMBL1191487 | 0.67 | MEN1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL8506879 | 0.67 | — | — | |
| Iodide SCHEMBL4003342 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137545-A | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | 美国安进公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-1028864-C | Macrolide compounds and their preparation | SANKYO CO (JP) | 1995-06-14 | — | — | CN | disclosed |
| US-5405867-A | Milbemycin derivatives with insecticidal and anthelmintic properties; for plants and animals | SANKYO COMPANY, LIMITED (JP) | 1995-04-11 | — | — | US | disclosed |
| CN-1022834-C | Macrolide compounds, their preparation and their use | SANKYO CO (JP) | 1993-11-24 | — | — | CN | disclosed |
| EP-0342710-B1 | MACROLIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-05-19 | — | — | EP | disclosed |
| CN-1071430-A | Macrolide bonded preparation method | SANKYO CO (JP) | 1993-04-28 | — | — | CN | disclosed |
| US-4963582-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO COMPANY LIMITED (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0342710-A1 | Macrolide compounds, their preparation and their use | Sankyo Company Limited (JP) | 1989-11-23 | — | — | EP | disclosed |
| CN-87103559-A | Macrolide compounds, their production and use | — | 1988-01-27 | — | — | CN | disclosed |
| EP-0246739-A2 | Macrolide compounds, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1987-11-25 | — | — | EP | disclosed |