Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 4/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253311 | 1.00 | KMT2A (0.41) | KMT2ASMN1; SMN2HTTTDP1F2 | |
| SCHEMBL9253303 | 1.00 | KMT2A (0.41) | KMT2ASMN1; SMN2HTTTDP1F2 | |
| SCHEMBL9257519 | 0.96 | KMT2A (0.44) | KMT2ASMN1; SMN2HTTTDP1F2 | |
| SCHEMBL9257522 | 0.96 | KMT2A (0.44) | KMT2ASMN1; SMN2HTTTDP1F2 | |
| SCHEMBL9256839 | 0.93 | KMT2A (0.43) | KMT2ASMN1; SMN2HTTTDP1F2 | |
| SCHEMBL9256841 | 0.93 | KMT2A (0.43) | KMT2ASMN1; SMN2HTTTDP1F2 | |
| SCHEMBL9256835 | 0.93 | KMT2A (0.43) | KMT2ASMN1; SMN2HTTTDP1F2 | |
| SCHEMBL9253545 | 0.89 | KMT2A (0.46) | KMT2ASMN1; SMN2HTTTDP1F2 | |
| SCHEMBL9253541 | 0.89 | KMT2A (0.46) | KMT2ASMN1; SMN2HTTTDP1F2 | |
| SCHEMBL9257968 | 0.88 | KMT2A (0.41) | KMT2ASMN1; SMN2HTTTDP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454974-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5230826-A | HALOBENZENE LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |
| US-5013477-A | Alkenylbicyclohexane liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | disclosed |