SCHEMBL9253340

SCHEMBL9253340

CCC1CCC(C2CCC(COc3ccc(F)cc3F)CC2)CC1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.47
HTR2C P28335 2/20 0.47
HTR2B P41595 2/20 0.47
BRD4 O60885 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
IDH2 P48735 1/20 0.39
RIPK1 Q13546 1/20 0.38
CHRNA7 P36544 1/20 0.38
TLR9 Q9NR96 1/20 0.38
TLR8 Q9NR97 1/20 0.38
TLR7 Q9NYK1 1/20 0.38
KDM1A O60341 2/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9253337 1.00 HTR2A (0.47) HTR2AHTR2CHTR2BBRD4KMT2A
SCHEMBL9260050 0.96 HTR2A (0.50) HTR2AHTR2CHTR2BBRD4KMT2A
SCHEMBL9260055 0.96 HTR2A (0.50) HTR2AHTR2CHTR2BBRD4KMT2A
SCHEMBL9257061 0.89 HTR2A (0.45) HTR2AHTR2CHTR2BBRD4KMT2A
SCHEMBL9257053 0.89 HTR2A (0.45) HTR2AHTR2CHTR2BBRD4KMT2A
SCHEMBL28333031 0.88 HTR2A (0.56) HTR2AHTR2CHTR2BBRD4KMT2A
SCHEMBL9249691 0.87 HTR2A (0.43) HTR2AHTR2CHTR2BBRD4KMT2A
SCHEMBL9249687 0.87 HTR2A (0.43) HTR2AHTR2CHTR2BBRD4KMT2A
SCHEMBL9254949 0.85 HTR2A (0.43) HTR2AHTR2CHTR2BBRD4KMT2A
SCHEMBL9254954 0.85 HTR2A (0.43) HTR2AHTR2CHTR2BBRD4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995009829-A1 2,4-DIFLUOROBENZENES AND THEIR USE IN LIQUID CRYSTAL MIXTURES MERCK PATENT GMBH (DE) 1995-04-13 WO disclosed