Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FER | P16591 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142142 | 0.71 | GSK3B (0.41) | GSK3BMAPTKMT2ALMNAMEN1 | |
| SCHEMBL28912687 | 0.70 | GRK6 (0.41) | KMT2AMEN1PPARGNCOR2USP2 | |
| SCHEMBL9255257 | 0.67 | GSK3B (0.37) | GSK3BMAPTKMT2ALMNAMEN1 | |
| SCHEMBL10974212 | 0.67 | GSK3B (0.37) | GSK3BMAPTKMT2ALMNAMEN1 | |
| SCHEMBL794250 | 0.67 | PARP11 (0.44) | GSK3BMAPTKMT2AMEN1GAA | |
| SCHEMBL334824 | 0.66 | GSK3B (0.44) | GSK3BMAPTKMT2ALMNAMEN1 | |
| SCHEMBL20504712 | 0.66 | GSK3B (0.44) | GSK3BMAPTKMT2ALMNAMEN1 | |
| SCHEMBL7980321 | 0.64 | MAPT (0.56) | GSK3BMAPTLMNAGAACASP3 | |
| SCHEMBL331978 | 0.64 | GSK3B (0.42) | GSK3BMAPTKMT2ALMNAMEN1 | |
| SCHEMBL27985053 | 0.63 | GRK6 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441948-A | Treatment of angina pectoris | EGIS GYOGYSZERGYAR RT. (HU) | 1995-08-15 | — | — | US | claimed |
| US-5441948-A | Treatment of angina pectoris | EGIS GYOGYSZERGYAR RT. (HU) | 1995-08-15 | — | — | US | disclosed |
| US-5441948-A | Treatment of angina pectoris | EGIS GYOGYSZERGYAR RT. (HU) | 1995-08-15 | — | — | US | disclosed |