Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253936 | 1.00 | PTAFR (0.53) | PTAFRKDM4EALDH1A1DRD2DRD3 | |
| SCHEMBL9253997 | 0.98 | PTAFR (0.52) | PTAFRKDM4EALDH1A1DRD2DRD3 | |
| SCHEMBL9253986 | 0.98 | PTAFR (0.52) | PTAFRKDM4EALDH1A1DRD2DRD3 | |
| SCHEMBL9667466 | 0.97 | PTAFR (0.51) | PTAFRKDM4EALDH1A1DRD2DRD3 | |
| SCHEMBL9249446 | 0.97 | PTAFR (0.51) | PTAFRKDM4EALDH1A1DRD2DRD3 | |
| SCHEMBL9258510 | 0.95 | PTAFR (0.50) | PTAFRKDM4EALDH1A1 | |
| SCHEMBL9258514 | 0.95 | PTAFR (0.50) | PTAFRKDM4EALDH1A1 | |
| SCHEMBL9669731 | 0.93 | PTAFR (0.59) | PTAFRKDM4EALDH1A1DRD2DRD3 | |
| SCHEMBL9669732 | 0.93 | PTAFR (0.59) | PTAFRKDM4EALDH1A1DRD2DRD3 | |
| SCHEMBL9258677 | 0.90 | PTAFR (0.59) | PTAFRKDM4EALDH1A1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |