SCHEMBL9253984

SCHEMBL9253984

C=CC(=O)ONS(=O)(=O)O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.33
ALDH1A1 P00352 4/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29175484 0.79 TSHR (0.34) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL19725179 0.74 CA1 (0.38) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL18844904 0.71 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL3668715 0.70 HCAR2 (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL27656093 0.70 HCAR2 (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL27567444 0.70 HCAR2 (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL27504128 0.70 HCAR2 (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
Sulfuric Acid SCHEMBL9766441 0.69 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9254036 0.69
Acrylic Acid Methyl Ester SCHEMBL28102363 0.68 HCAR2 (0.43) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0491198-A1 Process for producing anti-wick polyester yarn BRIDGESTONE/FIRESTONE, INC. (US) 1992-06-24 EP claimed
US-5116682-A Coating with aqueous emulsion or dispersion of heat-curable polyfluorinated polymer, drying without the coating contacting any surface, heat curing BRIDGESTONE/FIRESTONE, INC. (US) 1992-05-26 US claimed
US-5439998-A Water and oil repellent ELF ATOCHEM (FR) 1995-08-08 US disclosed
EP-0491198-A1 Process for producing anti-wick polyester yarn BRIDGESTONE/FIRESTONE, INC. (US) 1992-06-24 EP disclosed
US-5116682-A Coating with aqueous emulsion or dispersion of heat-curable polyfluorinated polymer, drying without the coating contacting any surface, heat curing BRIDGESTONE/FIRESTONE, INC. (US) 1992-05-26 US disclosed