Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9252134 | 0.98 | MEN1 (0.69) | MEN1KMT2ACYP2D6SLC18A3MAPT | |
| SCHEMBL9486101 | 0.88 | MAPT (0.57) | MEN1KMT2ACYP2D6SLC18A3MAPT | |
| SCHEMBL29083049 | 0.84 | SRD5A2 (0.54) | MEN1KMT2ACYP2D6SLC18A3MAPT | |
| SCHEMBL1582773 | 0.81 | KMT2A (0.96) | MEN1KMT2ACYP2D6ALDH1A1HSD11B1 | |
| SCHEMBL7036133 | 0.80 | MEN1 (0.60) | MEN1KMT2ACYP2D6ALDH1A1HDAC3 | |
| Bromide SCHEMBL10968871 | 0.79 | KMT2A (0.93) | MEN1KMT2ACYP2D6ALDH1A1HSD11B1 | |
| Hydrochloric Acid SCHEMBL2366330 | 0.79 | KMT2A (1.00) | MEN1KMT2ACYP2D6ALDH1A1HSD11B1 | |
| SCHEMBL5218517 | 0.79 | MEN1 (0.69) | MEN1KMT2ACYP2D6RAB9ANPC1 | |
| SCHEMBL13944266 | 0.79 | MEN1 (0.69) | MEN1KMT2ACYP2D6HSD11B1RAB9A | |
| Hydrochloric Acid SCHEMBL20838548 | 0.78 | MEN1 (0.63) | MEN1KMT2ACYP2D6ALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441967-A | Treating cerebral edema; anticholinesterase or brain function-improving agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-15 | — | — | US | disclosed |
| CN-1024548-C | Cyclic amine compounds and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-05-18 | — | — | CN | disclosed |
| US-5294625-A | 1-benzyl,4-((4-dialkylaminophenyl)carbonyl)piperidines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0378207-B1 | CYCLIC AMINE COMPOUNDS AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-5177087-A | Cerebral edema, cholinesterase inhibitor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| CN-1053231-A | Cyclic amine compound and uses thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-07-24 | — | — | CN | disclosed |
| EP-0378207-A1 | Cyclic amine compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-18 | — | — | EP | disclosed |