Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31262962 | 0.82 | TSHR (0.55) | CA1CA2CA12CA9HRH3 | |
| SCHEMBL807665 | 0.80 | MAPT (0.48) | CA1CA2CA12CA9FFAR1 | |
| SCHEMBL31262950 | 0.80 | CA1 (0.44) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL23963287 | 0.80 | HRH3 (0.45) | CA1CA2CA12CA9HRH3 | |
| SCHEMBL7107232 | 0.80 | HRH3 (0.45) | CA1CA2CA12CA9HRH3 | |
| SCHEMBL4493412 | 0.79 | CA12 (0.46) | CA1CA2CA12CA9RAB9A | |
| SCHEMBL20762355 | 0.79 | CA12 (0.43) | CA1CA2CA12CA9HRH3 | |
| SCHEMBL31263081 | 0.79 | MAPT (0.44) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL11622277 | 0.78 | CA1 (0.44) | CA1CA2FFAR1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11841695 | 0.78 | CA1 (0.44) | CA1CA2FFAR1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432194-A | Antiallergens, antinflammatory agents | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |
| US-5346914-A | Antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-09-13 | — | — | US | disclosed |