⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL5827378 | 0.97 | — | — | |
| Chloromethane SCHEMBL869309 | 0.77 | — | — | |
| SCHEMBL39952 | 0.76 | — | — | |
| SCHEMBL9694230 | 0.76 | — | — | |
| SCHEMBL7893787 | 0.72 | — | — | |
| Water SCHEMBL5555452 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL1093323 | 0.72 | — | — | |
| SCHEMBL2256872 | 0.72 | — | — | |
| SCHEMBL4385577 | 0.72 | — | — | |
| Bromide SCHEMBL1835600 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288793-B | The Phenethanolamine derivative for the treatment of respiratory disease | GLAXO GROUP LTD. (GB) | 2015-09-23 | — | — | CN | disclosed |
| US-RE44874-E1 | Phenethanolamine derivatives for treatment of respiratory diseases | GLAXO GROUP LIMITED (GB) | 2014-04-29 | — | — | US | disclosed |
| CN-101701006-B | Phenethanolamine derivatives for treatment of respiratory diseases | GLAXO GROUP LTD | 2014-03-05 | — | — | CN | disclosed |
| EP-2042168-B1 | Inhalation formulation comprising phenethanolamine derivatives for the treatment of respiratory diseases | GLAXO GROUP LTD (GB) | 2013-10-23 | — | — | EP | disclosed |
| CN-103288793-A | Phenethanolamine derivatives for treatment of respiratory diseases | GLAXO GROUP LTD | 2013-09-11 | — | — | CN | disclosed |
| US-8198483-B2 | Phenethanolamine derivatives for treatment of respiratory diseases | GLAXO GROUP LIMITED (GB) | 2012-06-12 | — | — | US | disclosed |
| US-20110269970-A1 | Phenethanolamine Derivatives for Treatment of Respiratory Diseases | GLAXO GROUP LIMITED (GB) | 2011-11-03 | — | — | US | disclosed |
| US-7982067-B2 | Phenethanolamine derivatives for treatment of respiratory diseases | GLAXO GROUP LIMITED (GB) | 2011-07-19 | — | — | US | disclosed |
| US-20110009631-A1 | Phenethanolamine Derivatives for Treatment of Respiratory Diseases | GLAXO GROUP LIMITED (GB) | 2011-01-13 | — | — | US | disclosed |
| CN-1585633-B | Phenylethanolamine derivatives for the treatment of respiratory diseases | GLAXO GROUP LTD | 2010-10-27 | — | — | CN | disclosed |
| WO-1994008993-A1 | BENZOFURAN DERIVATIVES AS 5-HT1-LIKE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1994-04-28 | — | — | WO | disclosed |
| US-5114945-A | Spiropiperidine derivatives | GLAXO GROUP LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| US-4923865-A | Substituted 1-(1H-imidazol-4-yl)alkyl-benzamides as anti-ischemics and as alpha-2-adrenergic receptor agonists | U C B SOCIETE ANONYME (BE) | 1990-05-08 | — | — | US | disclosed |
| WO-1989008116-A1 | 16-HOMO PIPERIDINO ANDROSTANES AND THEIR PREPARATION | AKZO N.V. (NL) | 1989-09-08 | — | — | WO | disclosed |
| EP-0330461-A2 | Piperidine derivatives | GLAXO GROUP LIMITED (GB) | 1989-08-30 | — | — | EP | disclosed |
| EP-0330253-A1 | Novel 16-homo-piperidino-androstane derivatives and processes for their preparation | AKZO N.V. (NL) | 1989-08-30 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0155721-B1 | NOVEL ANTI-ARRHYTHMIC AMINO-ALCOHOLS | AKZO N.V. (NL) | 1987-09-23 | — | — | EP | disclosed |
| US-4613619-A | Anti-arrhythmic amino-alcohols | AKZO N.V. (NL) | 1986-09-23 | — | — | US | disclosed |
| EP-0155721-A1 | Novel anti-arrhythmic amino-alcohols | AKZO N.V. (NL) | 1985-09-25 | — | — | EP | disclosed |